Kruis score is the sum of the weighted items below. Higher scores favour IBS and negative scores favour organic disease. A score of at least 44 points is considered positive in the original model.

Item	Response	Score
Symptoms of abdominal pain, bloating/flatulence or bowel irregularity	Yes	+34
Symptom duration >2 years	Yes	+16
Abdominal pain described as burning, cutting, very strong, terrible, pressure-like, dull, boring or not so bad	Yes	+23
Alternating constipation and diarrhoea	Yes	+14
Abnormal physical findings or history suggesting another diagnosis	Yes	-47
ESR >10 mm/h	Yes	-13
Leucocytosis >10 x 10^9/L or >10,000/microL	Yes	-50
Low haemoglobin: female below 120 g/L or male below 140 g/L	Yes	-98
History of blood in stool	Yes	-98

Total score range is approximately -306 to +87. Scores of at least 44 favour IBS. Lower scores favour organic gastrointestinal disease or insufficient rule-in evidence.

Kruis Score for Diagnosis of Irritable Bowel Syndrome (IBS)